購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱：小鼠抗ACLY(C-term)單克隆抗體
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Background: |
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. |
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Applications: |
WB, IF, FC |
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Name of antibody: |
ACLY(C-term) |
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Immunogen: |
Fusion protein of human ACLY |
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Full name: |
ATP citrate lyase |
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Synonyms: |
ACL; ATPCL; CLATP |
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SwissProt: |
P53396 |
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WB Predicted band size: |
121 kDa |
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WB Positive control: |
Hela, K562, COS7 and 3T3 cell lysates |
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WB Recommended dilution: |
1000-5000 |
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IF positive control: |
Hela cells |
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IF Recommend dilution: |
50-150 |
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FC Recommend dilution: |
50-100 |
