購物車
幫助
021-54845833/15800441009
中文名稱： UBA7 抗原（重組蛋白）
英文名稱： UBA7 Antigen (Recombinant Protein)
別 名： ubiquitin like modifier activating enzyme 7; D8; UBE2; UBA1B; UBE1L
儲 存： 冷凍（-20℃）
相關類別：抗原
概 述
|
Full name: |
ubiquitin like modifier activating enzyme 7 |
|
Synonyms: |
D8; UBE2; UBA1B; UBE1L |
|
Swissprot: |
P41226 |
|
Gene Accession: |
BC006378 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. |
