購物車
幫助
021-54845833/15800441009
中文名稱： TRPC4AP 抗原（重組蛋白）
英文名稱： TRPC4AP Antigen (Recombinant Protein)
別 名： transient receptor potential cation channel, subfamily C, member 4 associated protein; TRUSS; TRRP4AP; PPP1R158; C20orf188
儲 存： 冷凍（-20℃）
相關類別：抗原
概 述
|
Full name: |
transient receptor potential cation channel, subfamily C, member 4 associated protein |
|
Synonyms: |
TRUSS; TRRP4AP; PPP1R158; C20orf188 |
|
Swissprot: |
Q8TEL6 |
|
Gene Accession: |
BC013144 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
TRPC4AP (transient receptor potential cation channel, subfamily C, member 4 associated protein), also known as TRUSS or TRRP4AP, is a 797 amino acid protein that is expressed in a variety of tissues, with highest expression in liver, heart, testis and brain. Thought to function as a scaffolding protein, TRPC4AP interacts with TNF-R1 and may both link TNF-R1 to the IKK signalsome complex, and participate in the activation of NFκB p50, an event that occurs in response to TNF-R1 ligation. TRPC4AP exists as multiple alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 20. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. |
