中文名稱: TNFAIP3 抗原(重組蛋白)
英文名稱: TNFAIP3 Antigen (Recombinant Protein)
別 名: TNF alpha induced protein 3; A20; AISBL; OTUD7C; TNFA1P2
儲 存: 冷凍(-20℃)
相關類別:抗原
概 述
Full name: |
TNF alpha induced protein 3 |
Synonyms: |
A20; AISBL; OTUD7C; TNFA1P2 |
Swissprot: |
P21580 |
Gene Accession: |
BC114480 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene. |