中文名稱:兔抗CDK14多克隆抗體
英文名稱: Anti-CDK14 rabbit polyclonal antibody
別 名: PFTK1; PFTAIRE1
相關類別: 一抗
儲 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: CDK14
反應種屬: Human, Mouse
標 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術規格
Background: |
Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
CDK14 |
Immunogen: |
Synthetic peptide of human CDK14 |
Full name: |
cyclin-dependent kinase 14 |
Synonyms: |
PFTK1; PFTAIRE1 |
SwissProt: |
O94921 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human liver cancer |
IHC Recommend dilution: |
20-100 |
WB Predicted band size: |
53 kDa |
WB Positive control: |
Mouse Pancreas tissue lysate |
WB Recommended dilution: |
200-1000 |