中文名稱: 兔抗CACNB4多克隆抗體
英文名稱: Anti-CACNB4 rabbit polyclonal antibody
別 名: EA5; EJM; CAB4; EIG9; EJM4; EJM6; CACNLB4
儲 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: CACNB4
反應(yīng)種屬: Human, Mouse, Rat
相關(guān)類別: 一抗
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME). Multiple transcript variants encoding different isoforms have been found for this gene. |
Applications: |
ELISA, WB |
Name of antibody: |
CACNB4 |
Immunogen: |
Synthetic peptide of human CACNB4 |
Full name: |
calcium voltage-gated channel auxiliary subunit beta 4 |
Synonyms: |
EA5; EJM; CAB4; EIG9; EJM4; EJM6; CACNLB4 |
SwissProt: |
O00305 |
ELISA Recommended dilution: |
5000-10000 |
WB Predicted band size: |
58 kDa |
WB Positive control: |
Mouse brain tissue lysate |
WB Recommended dilution: |
200-1000 |