中文名稱: 兔抗PIM2多克隆抗體
英文名稱: Anti-PIM2 rabbit polyclonal antibody
相關(guān)類別: 一抗
儲 存: 冷凍(-20℃)
抗 原: PIM2
宿 主: Rabbit
反應(yīng)種屬: Human, Mouse
標 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival. Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression, the regulation of cap-dependent protein translation and through survival signaling by phosphorylation of a pro-apoptotic protein, BAD. Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase transcriptional activity. |
Applications: |
ELISA, IHC |
Name of antibody: |
PIM2 |
Immunogen: |
Fusion protein of human PIM2 |
Full name: |
pim-2 oncogene |
SwissProt: |
Q9P1W9 |
ELISA Recommended dilution: |
1000-5000 |
IHC positive control: |
Human thyroid cancer |
IHC Recommend dilution: |
50-200 |