中文名稱: 兔抗PHKG2多克隆抗體
英文名稱: Anti-PHKG2 rabbit polyclonal antibody
別 名: phosphorylase kinase catalytic subunit gamma 2; GSD9C
抗 原: PHKG2
儲 存: 冷凍(-20℃)
宿 主: Rabbit
反應種屬: Human, Mouse, Rat
相關類別: 一抗
標 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術規格
Background: |
Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9C, also known as autosomal liver glycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. |
Applications: |
ELISA, IHC |
Name of antibody: |
PHKG2 |
Immunogen: |
Fusion protein of human PHKG2 |
Full name: |
phosphorylase kinase catalytic subunit gamma 2 |
Synonyms: |
GSD9C |
SwissProt: |
P15735 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human tonsil and Human liver cancer |
IHC Recommend dilution: |
50-300 |