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英文名稱： Anti-RPA2(Phospho-Thr21) rabbit polyclonal
antibody
別 名： REPA2; RPA32; RP-A p32; RP-A p34
相關(guān)類別： 一抗
儲 存： 冷凍（-20℃） 避光
宿 主： Rabbit
抗 原： RPA2(Phospho-Thr21)
反應種屬： Human Rat
標記物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. Required for the efficient recruitment of the DNA double-strand break repair factor RAD51 to chromatin in response to DNA damage. Ref.9 Ref.14 Ref.15 Ref.16 Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair; it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange. |
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Applications: |
WB |
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Name of antibody: |
RPA2(Phospho-Thr21) |
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Immunogen: |
Peptide sequence around phosphorylation site of Threonine 21 (G-Y-T(p)-Q-S) derived from Human RFA2. |
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Full name: |
replication protein A2, 32kDa |
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Synonyms： |
REPA2; RPA32; RP-A p32; RP-A p34 |
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SwissProt: |
P15927 |
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WB Predicted band size: |
29 kDa |
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WB Positive control: |
Rat heart tissue lysates |
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WB Recommended dilution: |
500-1000 |
