中文名稱：兔抗F10多克隆抗體

英文名稱： Anti-F10 rabbit polyclonal antibody

別名： FX; FXA

抗原： F10

儲存： 冷凍（-20℃）

宿主： Rabbit

相關(guān)類別： 一抗

反應(yīng)種屬： Human, Mouse, Rat

標記物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.

Applications:

ELISA, WB

Name of antibody:

F10

Immunogen:

Fusion protein of human F10

Full name:

Coagulation factor X

Synonyms：

FX; FXA

SwissProt:

P00742

ELISA Recommended dilution:

1000-2000

WB Predicted band size:

55 kDa

WB Positive control:

A549 cells

WB Recommended dilution:

200-1000

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兔抗F10多克隆抗體說明書
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兔抗F10多克隆抗體

Background:	This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.
Applications:	ELISA, WB
Name of antibody:	F10
Immunogen:	Fusion protein of human F10
Full name:	Coagulation factor X
Synonyms：	FX; FXA
SwissProt:	P00742
ELISA Recommended dilution:	1000-2000
WB Predicted band size:	55 kDa
WB Positive control:	A549 cells
WB Recommended dilution:	200-1000