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中文名稱：PEPD抗原（重組蛋白）
英文名稱： PEPD Antigen (Recombinant Protein)
別 名： PROLIDASE
儲 存： 冷凍（-20℃）
相關類別： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 294-493 amino acids of human PEPD |
|
Full name: |
peptidase D |
|
Synonyms: |
PROLIDASE |
|
Swissprot: |
P12955 |
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Gene Accession: |
BC028295 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the peptidase family. The protein forms a homodimer that hydrolyzes dipeptides or tripeptides with C-terminal proline or hydroxyproline residues. The enzyme serves an important role in the recycling of proline, and may be rate limiting for the production of collagen. Mutations in this gene result in prolidase deficiency, which is characterized by the excretion of large amount of di- and tri-peptides containing proline. Multiple transcript variants encoding different isoforms have been found for this gene. |
