中文名稱:OSBPL2抗原(重組蛋白)
英文名稱: OSBPL2 Antigen (Recombinant Protein)
別 名: ORP2; ORP-2; DFNA67; DNFA67
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 281-480 amino acids of human OSBPL2 |
Full name: |
oxysterol binding protein like 2 |
Synonyms: |
ORP2; ORP-2; DFNA67; DNFA67 |
Swissprot: |
Q9H1P3 |
Gene Accession: |
BC000296 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although the encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. |