Name: POLDIP3抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： POLDIP3抗原（重組蛋白）

英文名稱： POLDIP3 Antigen (Recombinant Protein)

別名： polymerase (DNA-directed), delta interacting protein 3; SKAR; PDIP46

相關(guān)類別：抗原

儲存： 冷凍（-20℃）

概述

Fusion protein corresponding to a region derived from 36-229 amino acids of human POLDIP3

技術(shù)規(guī)格

Full name:	polymerase (DNA-directed), delta interacting protein 3
Synonyms:	SKAR; PDIP46
Swissprot:	Q9BY77
Gene Accession:	BC019643
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	POLDIP3 (polymerase delta-interacting protein 3), also known as SKAR or PDIP46, is a 421 amino acid nuclear protein. POLDIP3 interacts with DNA pol ? 2, a protein essential to DNA replication, recombination and repair. POLDIP3 is a substrate for the signaling intermediate Rsk-1 and is thought to regulate cell growth. POLDIP3 contains one RRM (RNA recognition motif) domain and is phosphorylated upon DNA damage. POLDIP3 is ubiquitously expressed with highest levels found in heart, kidney, skeletal muscle and brain. Due to alternative splicing, POLDIP3 is expressed as two isoforms.

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