購物車
幫助
021-54845833/15800441009
中文名稱：IRAK4抗原（重組蛋白）
英文名稱： IRAK4 Antigen (Recombinant Protein)
別 名： IPD1; REN64; IRAK-4; NY-REN-64
儲 存： 冷凍（-20℃）
相關類別： 抗原
概述
|
usion protein corresponding to a region derived from 186-454 amino acids of human IRAK4 |
|
Full name: |
interleukin-1 receptor-associated kinase 4 |
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Synonyms: |
IPD1; REN64; IRAK-4; NY-REN-64 |
|
Swissprot: |
Q9NWZ3 |
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Gene Accession: |
BC013316 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. |
