中文名稱(chēng):IL13RA1抗原(重組蛋白)
英文名稱(chēng): IL13RA1 Antigen (Recombinant Protein)
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類(lèi)別: 抗原
概述
Fusion protein corresponding to a region derived from 24-363 amino acids of human IL13RA1 |
技術(shù)規(guī)格
Full name: |
interleukin 13 receptor subunit alpha 1 |
Synonyms: |
NR4; CT19; CD213A1; IL-13Ra |
Swissprot: |
P78552 |
Gene Accession: |
BC015768 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. |