中文名稱:TAX1BP1 抗原(重組蛋白)
英文名稱: TAX1BP1 Antigen (Recombinant Protein)
別 名: Tax1 (human T-cell leukemia virus type I) binding protein 1; T6BP; TXBP151; CALCOCO3
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 180-420 amino acids of human TAX1BP1 |
Full name: |
Tax1 (human T-cell leukemia virus type I) binding protein 1 |
Synonyms: |
T6BP; TXBP151; CALCOCO3 |
Swissprot: |
Q86VP1 |
Gene Accession: |
BC050358 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[ |