中文名稱: SIGLEC5抗原(重組蛋白)
英文名稱: SIGLEC5 Antigen (Recombinant Protein)
別 名:CD170; OBBP2; CD33L2; OB-BP2; SIGLEC-5
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 19-229 amino acids of human SIGLEC5 |
Full name: |
sialic acid binding Ig-like lectin 5 |
Synonyms: |
CD170; OBBP2; CD33L2; OB-BP2; SIGLEC-5 |
Swissprot: |
O15389 |
Gene Accession: |
BC029896 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. |