Name: PRAME 抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： PRAME 抗原（重組蛋白）

英文名稱： PRAME Antigen (Recombinant Protein)

別名： preferentially expressed antigen in melanoma; MAPE; OIP4; CT130; OIP-4

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述

Fusion protein corresponding to a region derived from 260-509 amino acids of human PRAME

技術(shù)規(guī)格

Full name:	preferentially expressed antigen in melanoma
Synonyms:	MAPE; OIP4; CT130; OIP-4
Swissprot:	P78395
Gene Accession:	BC014074
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.

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