購(gòu)物車
幫助
021-54845833/15800441009
中文名稱： GADD45A抗原（重組蛋白）
英文名稱： GADD45A Antigen (Recombinant Protein)
別 名： DDIT1; GADD45
儲(chǔ) 存： 冷凍（-20℃）
相關(guān)類別： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 5-165 amino acids of human GADD45A |
|
Full name: |
growth arrest and DNA-damage-inducible, alpha |
|
Synonyms: |
DDIT1; GADD45 |
|
Swissprot: |
P24522 |
|
Gene Accession: |
BC011757 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
