中文名稱:ABCB6 抗原(重組蛋白)
英文名稱: ABCB6 Antigen (Recombinant Protein)
別 名: ATP-binding cassette, sub-family B (MDR/TAP), member 6; ABC; LAN; PRP; umat; ABC14; MTABC3; MCOPCB7
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 590-824 amino acids of human ABCB6 |
Full name: |
ATP-binding cassette, sub-family B (MDR/TAP), member 6 |
Synonyms: |
ABC; LAN; PRP; umat; ABC14; MTABC3; MCOPCB7 |
Swissprot: |
Q9NP58 |
Gene Accession: |
BC000559 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function. |