克隆類型: mouse monoclonal
技術規格
Background: |
This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Mar 2010]. |
Applications: |
WB, IF |
Name of antibody: |
POU5F1 |
Immunogen: |
Fusion protein of human POU5F1 |
Full name: |
POU class 5 homeobox 1 (POU5F1), transcript variant 1 |
Synonyms: |
Oct-3; Oct-4; OCT3; OCT4; OTF-3; OTF3; OTF4 |
SwissProt: |
Q01860 |
WB Predicted band size: |
39 kDa |
WB Positive control: |
Hela, SVT2, A549, PC12, MCF-7 cell lysates |
WB Recommended dilution: |
200-1000 |