技術規(guī)格
Background: |
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. |
Applications: |
ELISA, IHC |
Name of antibody: |
KEAP1 |
Immunogen: |
Synthetic peptide of human KEAP1 |
Full name: |
kelch-like ECH-associated protein 1 |
Synonyms: |
INrf2; KLHL19 |
SwissProt: |
Q14145 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human thyroid cancer and Human esophagus cancer |
IHC Recommend dilution: |
25-100 |