技術規格
Background: |
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. |
Applications: |
WB, IHC |
Name of antibody: |
ITGB1(Phospho-Thr789) |
Immunogen: |
Peptide sequence around phosphorylation site of threonine 789(V-E-T(p)-V-V) derived from Human Integrin β1 . |
Full name: |
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
Synonyms: |
CD29; FNRB; MDF2; VLAB; GPIIA; MSK12; VLA-BETA |
SwissProt: |
P05556 |
IHC positive control: |
Human breast carcinoma tissue |
IHC Recommend dilution: |
50-100 |
WB Predicted band size: |
88 kDa |
WB Positive control: |
HepG2 cells lysates treated with Ca2+ |
WB Recommended dilution: |
500-1000 |